Tracing dividing stem cells
نویسندگان
چکیده
منابع مشابه
In Vivo Tracing of Human Umbilical Cord Matrix Stem Cells Useing MRI
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Marking replicating DNA with multiple labels presents the possibility of revealing new features and mechanisms of DNA synthesis and cell division; however, progression beyond double labeling has been hampered by cross-reactivity of label detection and scarcity of appropriate labels. Here, we present a method for triple S-phase labeling of the dividing cells, with a fourth label used to mark cel...
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than inhibiting cell division? The quest to identify means to stop cells from proliferating has driven generations of researchers to investigate the mechanisms regulating the cell division cycle. The cell cycle consists of several phases. Progression from one phase to the next depends on the activity of specific proteins. In order to pass the checkpoints between two phases, several classes of p...
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Epithelia ensure many critical functions of the body, including protection against the external environment, nutrition, respiration, and reproduction. Stem cells (SCs) located in the various epithelia ensure the homeostasis and repair of these tissues throughout the lifetime of the animal. Genetic lineage tracing in mice has allowed the labeling of SCs and their progeny. This technique has been...
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ژورنال
عنوان ژورنال: Aging
سال: 2018
ISSN: 1945-4589
DOI: 10.18632/aging.101491